[HTML][HTML] Estradiol signaling at the heart of folliculogenesis: its potential deregulation in human ovarian pathologies

S Chauvin, J Cohen-Tannoudji, CJ Guigon - International journal of …, 2022 - mdpi.com
… in estrogen metabolism and biosynthesis [93]. Although we cannot assume that changes in
gene expression equate to altered protein expression … in up-regulating apoptotic genes [164]. …

[HTML][HTML] Natural resveratrol analogs differentially target endometriotic cells into apoptosis pathways

A Gołąbek-Grenda, M Kaczmarek, W Juzwa… - Scientific Reports, 2023 - nature.com
… The most potent up-regulating effect was observed under … proliferation and migration of
vascular endothelial cells. As a … -2 expression presumably through genomic estrogen signaling …

Roles of pigment epithelium-derived factor in cardiomyocytes: implications for use as a cardioprotective therapeutic

IC Jones, CR Dass - Journal of Pharmacy and Pharmacology, 2023 - academic.oup.com
… This review provides an overview of cardiac diseaseapoptosis of VEGF-stimulated rat aortic
endothelial cells. [37] … , PEDF is constitutively expressed in normal human cardiac tissue. [74…

Targeting chronic inflammation as a potential adjuvant therapy for osteoporosis

G Livshits, A Kalinkovich - Life Sciences, 2022 - Elsevier
… severe disorders, including cardiovascular disease, cancer, … indicates the capability of
estrogen to regulate various facets … For example, in a co-culture of neutrophils, endothelial cells, …

[HTML][HTML] Role of endoplasmic reticulum stress in atherosclerosis and its potential as a therapeutic target

S Yang, M Wu, X Li, R Zhao, Y Zhao, L Liu… - … Medicine and Cellular …, 2020 - hindawi.com
… could increase the expression of TLR2 in epithelial cells. … Estrogen significantly inhibited
the increase in p-PERK/PERK… mic reticulum stress in cardiovascular disease and exercise,” …

Cell death in atherosclerosis

D Ni, C Lei, M Liu, J Peng, G Yi, Z Mo - Cell Cycle, 2024 - Taylor & Francis
… and the apoptosis of endothelial cells, smooth muscle cells, and … Cardiovascular disease
is a precursor to endothelialendothelial ferroptosis, and the protective impact of estradiol on …

[HTML][HTML] Endoplasmic reticulum stress-mediated cell death in cardiovascular disease

Y An, X Wang, X Guan, P Yuan, Y Liu, L Wei… - Cell Stress and …, 2024 - Elsevier
… eIF2α, selectively up-regulating the translation of activating … brain ERS, suggesting that
estrogen protects women from Ang II-… ERS induces endothelial cell apoptosis through the CHOP …

The mitochondrial signature of cultured endothelial cells in sepsis: Identifying potential targets for treatment

A Montero-Jodra, MÁ de la Fuente, D Gobelli… - … Basis of Disease, 2024 - Elsevier
… Drp1 has been reported to increase the expression of Pink1 and … The nuclear estrogen-related
receptor alpha (receptor ERRα… , Fas or TNF receptors lead to apoptosis via ligand binding …

[HTML][HTML] Apoptosis in the extraosseous calcification process

F Boraldi, FD Lofaro, D Quaglino - Cells, 2021 - mdpi.com
… of vascular diseases, can induce endothelial cell apoptosis … , coronary artery disease,
and end-stage renal disease under … the expression of calcification-related genes by up-regulating

Flavonoids in adipose tissue inflammation and atherosclerosis: one arrow, two targets

MM Fardoun, D Maaliki, N Halabi, R Iratni… - Clinical …, 2020 - portlandpress.com
… Immunofluorescent staining in mouse tubular epithelial cells … flavonoid consumption and
cardiovascular disease (CVD) or … interactions by up-regulating adhesion molecules [18]. In …